What the FDA labels say about taking them together
Fluconazole and pacritinib
Pacritinib's FDA label of July 30, 2026 names fluconazole in its drug interactions section; the fluconazole labels PlainMeds reads (2) do not name pacritinib. The pacritinib label: “Monitor patients concomitantly receiving moderate CYP3A4 inhibitors (e.g., fluconazole) for increased adverse reactions and consider VONJO dose modifications based on safety.”
Check it at the source: the fluconazole FDA label on DailyMed (effective April 7, 2026, Zydus Pharmaceuticals (USA) Inc.); the pacritinib FDA label on DailyMed (effective July 30, 2026, Sobi, Inc.).
What does the fluconazole label say about pacritinib?
Fluconazole's label (effective April 7, 2026) and its 1 other brand-application label do not name pacritinib in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (fluconazole), Zydus Pharmaceuticals (USA) Inc., effective April 7, 2026 (SPL set d1364455-1537-46d4-b093-38cca3be778f), via openFDA; the full label on DailyMed
What does the pacritinib label say about fluconazole?
Pacritinib label, drug interactionsMonitor patients concomitantly receiving moderate CYP3A4 inhibitors (e.g., fluconazole) for increased adverse reactions and consider VONJO dose modifications based on safety [see Dosage and Administration ( 2.5 )].
Source: FDA drug label (Vonjo), Sobi, Inc., effective July 30, 2026 (SPL set 4b5ab444-0e1a-4984-99db-76ad11a298ee), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Fluconazole | Pacritinib | |
|---|---|---|
| Labeled for | Fungal infections, Urinary tract infections | n/a |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.380 per tablet 200 mg tablet | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once