Fluconazole · more major-labeled pairs than Amitriptyline

SPL labels Fluconazole + Amitriptyline as minor; Fluconazole 57 / Amitriptyline 20 in that band.

Mechanism on file: Fluconazole slows down how fast your body gets rid of amitriptyline, which can make the drug's effects stronger.

FDA SPL severity: Minor

Fluconazole

Full Fluconazole label record

Azole Antifungal

Amitriptyline

Full Amitriptyline label record

Tricyclic Antidepressant (TCA)

Fluconazole + Amitriptyline · SPL mechanism field

Fluconazole slows down how fast your body gets rid of amitriptyline, which can make the drug's effects stronger.

Minor band excerpt · Fluconazole with Amitriptyline

Amitriptyline, nortriptyline : Fluconazole increases the effect of amitriptyline and nortriptyline. 5-Nortriptyline and/or S-amitriptyline may be measured at initiation of the combination therapy and after 1 week. Dosage of amitriptyline/nortriptyline should be adjusted, if necessary.

Fluconazole · 3 major-labeled pairs (vs Amitriptyline's 1)

View all Fluconazole interactions →

Amitriptyline · 20 minor + 21 total pairs

View all Amitriptyline interactions →

FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.