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What the FDA labels say about taking them together

Fingolimod and ocrelizumab

Ocrelizumab's FDA label of May 14, 2026 names fingolimod in its drug interactions section; the fingolimod labels PlainMeds reads (2) do not name ocrelizumab.

Check it at the source: the fingolimod FDA label on DailyMed (effective July 22, 2026, Novartis Pharmaceuticals Corporation); the ocrelizumab FDA label on DailyMed (effective May 14, 2026, Genentech, Inc.).

What does the fingolimod label say about ocrelizumab?

Fingolimod's label (effective July 22, 2026) and its 1 other brand-application label do not name ocrelizumab in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Gilenya), Novartis Pharmaceuticals Corporation, effective July 22, 2026 (SPL set cc9e1c8c-0e2b-44e2-878b-27057f786be9), via openFDA; the full label on DailyMed

What does the ocrelizumab label say about fingolimod?

Ocrelizumab label, drug interactions

When switching from drugs with prolonged immune effects, such as daclizumab, fingolimod, natalizumab, teriflunomide, or mitoxantrone, consider the duration and mode of action of these drugs because of additive immunosuppressive effects when initiating OCREVUS [see Warnings and Precautions (5.2) ].

Ocrelizumab label, warnings and precautions

In the pediatric study, infections occurred in 73% of patients treated with OCREVUS (1.5 infections per patient-year) and 59% of patients treated with fingolimod (1.2 infections per patient-year) [see Adverse Reactions (6.1) ].

Source: FDA drug label (OCREVUS), Genentech, Inc., effective May 14, 2026 (SPL set 9da42362-3bb5-4b83-b4bb-b59fd4e55f0d), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

21Fingolimod generic labelers
0Ocrelizumab generic labelers
FingolimodOcrelizumab
Labeled forMultiple sclerosisn/a
Boxed warningNoNo
Pharmacy cost (NADAC)$1.58 per capsule 0.5 mg capsulen/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?