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What the FDA labels say about taking them together

Finerenone and itraconazole

Itraconazole's FDA label of July 13, 2026 names finerenone in its boxed warning section; the finerenone label PlainMeds reads does not name itraconazole. The itraconazole label: “Diuretics Eplerenone Finerenone Contraindicated during and 2 weeks after SPORANOX ® treatment.”

Check it at the source: the finerenone FDA label on DailyMed (effective August 28, 2025, Bayer HealthCare Pharmaceuticals Inc.); the itraconazole FDA label on DailyMed (effective July 13, 2026, Janssen Pharmaceuticals, Inc.).

What does the finerenone label say about itraconazole?

Finerenone's label (effective August 28, 2025) does not name itraconazole in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Kerendia), Bayer HealthCare Pharmaceuticals Inc., effective August 28, 2025 (SPL set fc726765-5d5a-4d6e-b037-b847bda9fb7c), via openFDA; the full label on DailyMed

What does the itraconazole label say about finerenone?

Itraconazole label, boxed warning

Some examples of drugs that are contraindicated for coadministration with SPORANOX ® Capsules are: methadone, disopyramide, dofetilide, dronedarone, quinidine, isavuconazole, ergot alkaloids (such as dihydroergotamine, ergometrine (ergonovine), ergotamine, methylergometrine (methylergonovine)), irinotecan, lurasidone, oral midazolam, pimozide, triazolam, felodipine, nisoldipine, ivabradine, ranolazine, eplerenone, cisapride, naloxegol, lomitapide, lovastatin, simvastatin, avanafil, ticagrelor, finerenone, voclosporin.

Itraconazole label, drug interactions

Diuretics Eplerenone Finerenone Contraindicated during and 2 weeks after SPORANOX ® treatment.

Source: FDA drug label (SPORANOX), Janssen Pharmaceuticals, Inc., effective July 13, 2026 (SPL set a4d555fa-787c-40fb-bb7d-b0d4f7318fd0), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Finerenone generic labelers
11Itraconazole generic labelers
FinerenoneItraconazole
Labeled forChronic kidney diseaseFungal infections
Boxed warningNoYes
Pharmacy cost (NADAC)$22.86 per tablet 10 mg tablet$0.910 per capsule 100 mg capsule
Shortage nowNo current entryA presentation being discontinued

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?