What the FDA labels say about taking them together
Fexinidazole and tinidazole
Fexinidazole's FDA label of May 2, 2025 names tinidazole in its contraindications section; the tinidazole label PlainMeds reads does not name fexinidazole. The fexinidazole label: “CONTRAINDICATIONS Fexinidazole Tablets are contraindicated in: Patients with known hypersensitivity to Fexinidazole Tablets and/or any nitroimidazole-class drugs.”
Check it at the source: the fexinidazole FDA label on DailyMed (effective May 2, 2025, Sanofi-Aventis U.S. LLC); the tinidazole FDA label on DailyMed (effective December 27, 2021, Mission Pharmacal Company).
What does the fexinidazole label say about tinidazole?
Fexinidazole label, contraindicationsCONTRAINDICATIONS Fexinidazole Tablets are contraindicated in: Patients with known hypersensitivity to Fexinidazole Tablets and/or any nitroimidazole-class drugs (e.g., metronidazole, tinidazole).
Source: FDA drug label (Fexinidazole), Sanofi-Aventis U.S. LLC, effective May 2, 2025 (SPL set 74a611bc-9977-46bb-b626-0370b3031628), via openFDA; the full label on DailyMed
What does the tinidazole label say about fexinidazole?
Tinidazole's label (effective December 27, 2021) does not name fexinidazole in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Tindamax), Mission Pharmacal Company, effective December 27, 2021 (SPL set a0d01539-8413-4703-94cc-d221918630a1), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Fexinidazole | Tinidazole | |
|---|---|---|
| Labeled for | n/a | n/a |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | n/a | $2.35 per tablet 500 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once