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What the FDA labels say about taking them together

Cimetidine and fesoterodine

Fesoterodine's FDA label of April 7, 2026 names cimetidine in its drug interactions section; the cimetidine label PlainMeds reads does not name fesoterodine.

Check it at the source: the cimetidine FDA label on DailyMed (effective July 15, 2026, Mylan Pharmaceuticals Inc.); the fesoterodine FDA label on DailyMed (effective April 7, 2026, Pfizer Laboratories Div Pfizer Inc).

What does the cimetidine label say about fesoterodine?

Cimetidine's label (effective July 15, 2026) does not name fesoterodine in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Cimetidine), Mylan Pharmaceuticals Inc., effective July 15, 2026 (SPL set 06c0a509-026f-44e0-9975-a94a8de51d43), via openFDA; the full label on DailyMed

What does the fesoterodine label say about cimetidine?

Fesoterodine label, drug interactions

The effect of weak CYP3A4 inhibitors (e.g. cimetidine) was not examined; it is not expected to be in excess of the effect of moderate inhibitors [see Clinical Pharmacology (12.3) ].

Source: FDA drug label (Toviaz), Pfizer Laboratories Div Pfizer Inc, effective April 7, 2026 (SPL set 5be745f0-8ae7-4c3c-9962-37d6263326f1), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

18Cimetidine generic labelers
11Fesoterodine generic labelers
CimetidineFesoterodine
Labeled forAcid reflux and ulcersOveractive bladder
Boxed warningNoNo
Pharmacy cost (NADAC)$0.236 per tablet 300 mg tablet$0.794 per tablet 4 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?