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What the FDA labels say about taking them together

Ferric oxyhydroxide and omeprazole

Ferric oxyhydroxide's FDA label of April 1, 2026 names omeprazole in its drug interactions section; the omeprazole labels PlainMeds reads (2) do not name ferric oxyhydroxide.

Check it at the source: the ferric oxyhydroxide FDA label on DailyMed (effective April 1, 2026, Fresenius Medical Care Renal Therapies Group, LLC); the omeprazole FDA label on DailyMed (effective April 22, 2024, Apotex Corp).

What does the ferric oxyhydroxide label say about omeprazole?

Ferric oxyhydroxide label, drug interactions

DRUG INTERACTIONS Table 1 Oral drugs that can be administered concomitantly with Velphoro Calcitriol Ciprofloxacin Digoxin Enalapril Furosemide HMG-CoA reductase inhibitors Hydrochlorothiazide Losartan Metoprolol Nifedipine Omeprazole Quinidine Warfarin Oral drugs that are to be separated from Velphoro Dosing Recommendations Doxycycline Acetylsalicylic acid Cephalexin Take at least 1 hour before Velphoro.

Source: FDA drug label (Velphoro), Fresenius Medical Care Renal Therapies Group, LLC, effective April 1, 2026 (SPL set 237da26c-f38c-4faa-93ad-735e71c9d0c1), via openFDA; the full label on DailyMed

What does the omeprazole label say about ferric oxyhydroxide?

Omeprazole's label (effective April 22, 2024) and its 1 other brand-application label do not name ferric oxyhydroxide in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Omeprazole), Apotex Corp, effective April 22, 2024 (SPL set b83329ac-a65e-b3af-a3fb-c5a6c740e5e7), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Ferric oxyhydroxide generic labelers
118Omeprazole generic labelers
Ferric oxyhydroxideOmeprazole
Labeled forn/aAcid reflux and ulcers
Boxed warningNoNo
Pharmacy cost (NADAC)$17.11 per tablet 500 mg chewable tablet$0.0295 per capsule 20 mg capsule
Shortage nowNo current entryA presentation being discontinued

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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