What the FDA labels say about taking them together
Ferric oxyhydroxide and metoprolol
Ferric oxyhydroxide's FDA label of April 1, 2026 names metoprolol in its drug interactions section; the metoprolol labels PlainMeds reads (4) do not name ferric oxyhydroxide.
Check it at the source: the ferric oxyhydroxide FDA label on DailyMed (effective April 1, 2026, Fresenius Medical Care Renal Therapies Group, LLC); the metoprolol FDA label on DailyMed (effective March 3, 2026, Melinta Therapeutics, LLC).
What does the ferric oxyhydroxide label say about metoprolol?
Ferric oxyhydroxide label, drug interactionsDRUG INTERACTIONS Table 1 Oral drugs that can be administered concomitantly with Velphoro Calcitriol Ciprofloxacin Digoxin Enalapril Furosemide HMG-CoA reductase inhibitors Hydrochlorothiazide Losartan Metoprolol Nifedipine Omeprazole Quinidine Warfarin Oral drugs that are to be separated from Velphoro Dosing Recommendations Doxycycline Acetylsalicylic acid Cephalexin Take at least 1 hour before Velphoro.
Source: FDA drug label (Velphoro), Fresenius Medical Care Renal Therapies Group, LLC, effective April 1, 2026 (SPL set 237da26c-f38c-4faa-93ad-735e71c9d0c1), via openFDA; the full label on DailyMed
What does the metoprolol label say about ferric oxyhydroxide?
Metoprolol's label (effective March 3, 2026) and its 3 other brand-application labels do not name ferric oxyhydroxide in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (TOPROL XL), Melinta Therapeutics, LLC, effective March 3, 2026 (SPL set 496ddfaa-7c9c-4888-b747-a210249b367a), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Ferric oxyhydroxide | Metoprolol | |
|---|---|---|
| Labeled for | n/a | High blood pressure, Angina, Heart failure, Heart attack and coronary artery disease |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $17.11 per tablet 500 mg chewable tablet | $0.085 per tablet 100 mg tablet |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once