What the FDA labels say about taking them together
Fentanyl and norepinephrine
Neither FDA label names the other in its interaction, contraindication or warning sections. A label lists the interactions its studies and reports found; it is not a complete list, so ask a pharmacist before combining medicines. Labels read October 8, 2026.
Check it at the source: the fentanyl FDA label on DailyMed (effective March 6, 2026, Hikma Pharmaceuticals USA Inc.); the norepinephrine FDA label on DailyMed (effective June 12, 2025, Hospira, Inc.).
What does the fentanyl label say about norepinephrine?
Fentanyl's label (effective March 6, 2026) and its 1 other brand-application label do not name norepinephrine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Fentanyl Citrate), Hikma Pharmaceuticals USA Inc., effective March 6, 2026 (SPL set ce5db1c2-feb1-4ad2-847a-d02e865bd47e), via openFDA; the full label on DailyMed
What does the norepinephrine label say about fentanyl?
Norepinephrine's label (effective June 12, 2025) and its 3 other brand-application labels do not name fentanyl in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (LEVOPHED), Hospira, Inc., effective June 12, 2025 (SPL set 2c7dd2b0-cc10-4db6-bf56-6eb154ebeb10), via openFDA; the full label on DailyMed
A pharmacist or prescriber can say whether these two medicines suit one person together; PlainMeds does not grade interactions.
Both medicines on the record
| Fentanyl | Norepinephrine | |
|---|---|---|
| Labeled for | Pain | n/a |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $1.79 per mL 100 mcg/2 mL vial | n/a |
| Shortage now | In shortage | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once