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What the FDA labels say about taking them together

Fentanyl and nevirapine

Nevirapine's FDA label of July 15, 2026 names fentanyl in its drug interactions section; the fentanyl labels PlainMeds reads (2) do not name nevirapine. The nevirapine label: “Opiate Agonists: Fentanyl Plasma concentrations may be decreased.”

Check it at the source: the fentanyl FDA label on DailyMed (effective March 6, 2026, Hikma Pharmaceuticals USA Inc.); the nevirapine FDA label on DailyMed (effective July 15, 2026, Mylan Pharmaceuticals Inc.).

What does the fentanyl label say about nevirapine?

Fentanyl's label (effective March 6, 2026) and its 1 other brand-application label do not name nevirapine in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Fentanyl Citrate), Hikma Pharmaceuticals USA Inc., effective March 6, 2026 (SPL set ce5db1c2-feb1-4ad2-847a-d02e865bd47e), via openFDA; the full label on DailyMed

What does the nevirapine label say about fentanyl?

Nevirapine label, drug interactions

Opiate Agonists: Fentanyl Plasma concentrations may be decreased.

Source: FDA drug label (Nevirapine), Mylan Pharmaceuticals Inc., effective July 15, 2026 (SPL set c6e93829-7024-48f6-8023-da6ff27dfc0a), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

6Fentanyl generic labelers
6Nevirapine generic labelers
FentanylNevirapine
Labeled forPainHIV
Boxed warningYesYes
Pharmacy cost (NADAC)$1.79 per mL 100 mcg/2 mL vial$0.147 per tablet 200 mg tablet
Shortage nowIn shortageNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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