What the FDA labels say about taking them together
Felbamate and norethindrone
Norethindrone's FDA label of January 31, 2026 names felbamate in its drug interactions section; the felbamate label PlainMeds reads does not name norethindrone. The norethindrone label: “This could result in unintended pregnancy or breakthrough bleeding. Examples include rifampin, barbiturates, phenylbutazone, phenytoin, carbamazepine, felbamate, oxcarbazepine, topiramate, and griseofulvin. b.”
Check it at the source: the felbamate FDA label on DailyMed (effective August 15, 2025, Viatris Specialty LLC); the norethindrone FDA label on DailyMed (effective January 31, 2026, Glenmark Pharmaceuticals Inc., USA).
What does the felbamate label say about norethindrone?
Felbamate's label (effective August 15, 2025) does not name norethindrone in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Felbatol), NDA020189 (Mylan Speciality Lp), as published by Viatris Specialty LLC, effective August 15, 2025 (SPL set 2f522701-397a-11de-8a39-0800200c9a66), via openFDA; the full label on DailyMed
What does the norethindrone label say about felbamate?
Norethindrone label, drug interactionsSome drugs or herbal products that may decrease the effectiveness of HCs include efavirenz, phenytoin, barbiturates, carbamazepine, bosentan, felbamate, griseofulvin, oxcarbazepine, rifampicin, rifabutin, rufinamide, aprepitant, and products containing St. John’s wort.
Nora Be label (Teva Pharmaceuticals, Inc., April 2, 2024), drug interactionsThis could result in unintended pregnancy or breakthrough bleeding. Examples include rifampin, barbiturates, phenylbutazone, phenytoin, carbamazepine, felbamate, oxcarbazepine, topiramate, and griseofulvin. b.
Source: FDA drug label (Nora Be, NDA017060), Teva Pharmaceuticals, Inc., effective April 2, 2024 (SPL set 426ac898-7745-4645-bf9b-bae319e260e8), via openFDA
Source: FDA drug label (Norethindrone), Glenmark Pharmaceuticals Inc., USA, effective January 31, 2026 (SPL set 0d2f8fea-3675-40d2-afd9-9fcb148dbd4b), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Felbamate | Norethindrone | |
|---|---|---|
| Labeled for | Seizures and epilepsy | Birth control |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $1.00 per tablet 600 mg tablet | $0.290 per tablet 5 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once