What the FDA labels say about taking them together
Fedratinib and thiamine
Fedratinib's FDA label of July 20, 2026 names thiamine in its boxed warning section; the thiamine label PlainMeds reads does not name fedratinib. The fedratinib label: “However, if thiamine levels are low, replete thiamine prior to starting treatment.”
Check it at the source: the fedratinib FDA label on DailyMed (effective July 20, 2026, Celgene Corporation); the thiamine FDA label on DailyMed (effective July 22, 2026, Sagent Pharmaceuticals).
What does the fedratinib label say about thiamine?
Fedratinib label, boxed warningWhile on treatment all patients should receive prophylaxis with daily oral thiamine and should have thiamine levels assessed as clinically indicated. If encephalopathy is suspected, immediately discontinue INREBIC and initiate parenteral thiamine.
Fedratinib label, warnings and precautionsHowever, if thiamine levels are low, replete thiamine prior to starting treatment.
Source: FDA drug label (Inrebic), NDA212327 (Bristol-Myers), as published by Celgene Corporation, effective July 20, 2026 (SPL set f0f55a2a-4e0c-4cba-8571-03e1424486d7), via openFDA; the full label on DailyMed
What does the thiamine label say about fedratinib?
Thiamine's label (effective July 22, 2026) does not name fedratinib in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (thiamine hydrochloride), Sagent Pharmaceuticals, effective July 22, 2026 (SPL set 5982cf83-01d6-4acb-8373-339079b8a76e), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Fedratinib | Thiamine | |
|---|---|---|
| Labeled for | n/a | n/a |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | n/a | $2.25 per mL 200 mg/2 mL vial |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once