What the FDA labels say about taking them together
Etravirine and fluvastatin
Etravirine's FDA label of August 15, 2023 names fluvastatin in its drug interactions section; the fluvastatin labels PlainMeds reads (2) do not name etravirine. The etravirine label: “Fluvastatin and pitavastatin are metabolized by CYP2C9 and co-administration with INTELENCE may result in higher plasma concentrations of the HMG-CoA reductase inhibitor. …”
Check it at the source: the etravirine FDA label on DailyMed (effective August 15, 2023, Janssen Products LP); the fluvastatin FDA label on DailyMed (effective April 21, 2025, Teva Pharmaceuticals USA, Inc.).
What does the etravirine label say about fluvastatin?
Etravirine label, drug interactionsConcomitant Drug Class/Drug Name: fluvastatin pitavastatin; Effect on Concentration of Etravirine or Concomitant Drug: ↑ fluvastatin ↑ pitavastatin; Clinical Comment: Fluvastatin and pitavastatin are metabolized by CYP2C9 and co-administration with INTELENCE may result in higher plasma concentrations of the HMG-CoA reductase inhibitor. Dose adjustments for these HMG-CoA reductase inhibitors may be necessary.
Source: FDA drug label (Intelence), Janssen Products LP, effective August 15, 2023 (SPL set 6a9cbc29-9f15-4b24-8d86-206b82887f3d), via openFDA; the full label on DailyMed
What does the fluvastatin label say about etravirine?
Fluvastatin's label (effective April 21, 2025) and its 1 other brand-application label do not name etravirine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Fluvastatin), Teva Pharmaceuticals USA, Inc., effective April 21, 2025 (SPL set aad8b373-0aec-4efb-8e61-3d8114b31127), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Etravirine | Fluvastatin | |
|---|---|---|
| Labeled for | HIV | High cholesterol |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $9.94 per tablet 200 mg tablet | $2.88 per tablet 80 mg tablet |
| Shortage now | A presentation being discontinued | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once