What the FDA labels say about taking them together
Etrasimod arginine and procainamide
Etrasimod arginine's FDA label of August 18, 2025 names procainamide in its drug interactions section; the procainamide label PlainMeds reads does not name etrasimod arginine. The etrasimod arginine label: “Prevention or Management; Seek the advice of a cardiologist before initiating VELSIPITY treatment with Class Ia, Class III anti-arrhythmic drugs, or other drugs that prolong the QT interval.”
Check it at the source: the etrasimod arginine FDA label on DailyMed (effective August 18, 2025, Pfizer Laboratories Div Pfizer Inc); the procainamide FDA label on DailyMed (effective February 17, 2025, Caplin Steriles Limited).
What does the etrasimod arginine label say about procainamide?
Etrasimod arginine label, drug interactionsPrevention or Management; Seek the advice of a cardiologist before initiating VELSIPITY treatment with Class Ia (e.g., quinidine, procainamide), Class III anti-arrhythmic drugs (e.g., amiodarone, sotalol), or other drugs that prolong the QT interval.
Source: FDA drug label (Velsipity), Pfizer Laboratories Div Pfizer Inc, effective August 18, 2025 (SPL set 65171e4a-d136-4abc-b08c-c40c1b486ff6), via openFDA; the full label on DailyMed
What does the procainamide label say about etrasimod arginine?
Procainamide's label (effective February 17, 2025) does not name etrasimod arginine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Procainamide Hydrochloride), Caplin Steriles Limited, effective February 17, 2025 (SPL set fcaa5e9a-3c8a-4796-aa87-626268b6cf60), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Etrasimod arginine | Procainamide | |
|---|---|---|
| Labeled for | Crohn's disease and ulcerative colitis | n/a |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | n/a | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once