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What the FDA labels say about taking them together

Etonogestrel and nevirapine

Etonogestrel's FDA label of May 28, 2026 names nevirapine in its drug interactions section; the nevirapine label PlainMeds reads does not name etonogestrel. The etonogestrel label: “Significant changes (increase or decrease) in the plasma concentrations of progestin have been noted in cases of co-administration with HIV protease inhibitors or with non-nucleoside reverse transcriptase inhibitors.”

Check it at the source: the etonogestrel FDA label on DailyMed (effective May 28, 2026, Organon LLC); the nevirapine FDA label on DailyMed (effective July 15, 2026, Mylan Pharmaceuticals Inc.).

What does the etonogestrel label say about nevirapine?

Etonogestrel label, drug interactions

Significant changes (increase or decrease) in the plasma concentrations of progestin have been noted in cases of co-administration with HIV protease inhibitors (decrease [e.g., nelfinavir] or increase [e.g., indinavir, ritonavir and ritonavir-boosted protease inhibitors]) or with non-nucleoside reverse transcriptase inhibitors (decrease [e.g., nevirapine, efavirenz] or increase [e.g., etravirine]).

Source: FDA drug label (Nexplanon), Organon LLC, effective May 28, 2026 (SPL set 487f8a62-e142-457c-97cc-2e398fde7594), via openFDA; the full label on DailyMed

What does the nevirapine label say about etonogestrel?

Nevirapine's label (effective July 15, 2026) does not name etonogestrel in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Nevirapine), Mylan Pharmaceuticals Inc., effective July 15, 2026 (SPL set c6e93829-7024-48f6-8023-da6ff27dfc0a), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Etonogestrel generic labelers
6Nevirapine generic labelers
EtonogestrelNevirapine
Labeled forBirth controlHIV
Boxed warningYesYes
Pharmacy cost (NADAC)n/a$0.147 per tablet 200 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?