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What the FDA labels say about taking them together

Cyclosporine and etonogestrel

Etonogestrel's FDA label of May 28, 2026 names cyclosporine in its drug interactions section; the cyclosporine labels PlainMeds reads (4) do not name etonogestrel. The etonogestrel label: “Consequently, plasma concentrations may either increase or decrease (for example, lamotrigine).”

Check it at the source: the cyclosporine FDA label on DailyMed (effective August 10, 2026, Novartis Pharmaceuticals Corporation); the etonogestrel FDA label on DailyMed (effective May 28, 2026, Organon LLC).

What does the cyclosporine label say about etonogestrel?

Cyclosporine's label (effective August 10, 2026) and its 3 other brand-application labels do not name etonogestrel in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Neoral), Novartis Pharmaceuticals Corporation, effective August 10, 2026 (SPL set 94461af3-11f1-4670-95d4-2965b9538ae3), via openFDA; the full label on DailyMed

What does the etonogestrel label say about cyclosporine?

Etonogestrel label, drug interactions

Consequently, plasma concentrations may either increase (for example, cyclosporine) or decrease (for example, lamotrigine).

Source: FDA drug label (Nexplanon), Organon LLC, effective May 28, 2026 (SPL set 487f8a62-e142-457c-97cc-2e398fde7594), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

14Cyclosporine generic labelers
0Etonogestrel generic labelers
CyclosporineEtonogestrel
Labeled forOrgan transplant rejection, Rheumatoid arthritisBirth control
Boxed warningYesYes
Pharmacy cost (NADAC)$1.04 per unit 0.05% eye emulsionn/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?