What the FDA labels say about taking them together
Ethinyl estradiol/norgestrel and ritonavir
Ethinyl estradiol/norgestrel's FDA label of December 5, 2025 names ritonavir in its contraindications section; the ritonavir label PlainMeds reads does not name ethinyl estradiol/norgestrel. The ethinyl estradiol/norgestrel label: “… receiving Hepatitis C drug combinations containing ombitasvir/paritaprevir/ritonavir, with or without dasabuvir, due to the potential for ALT elevations.”
Check it at the source: the ethinyl estradiol/norgestrel FDA label on DailyMed (effective December 5, 2025, Lupin Pharmaceuticals, Inc.); the ritonavir FDA label on DailyMed (effective July 23, 2026, AbbVie Inc.).
What does the ethinyl estradiol/norgestrel label say about ritonavir?
Ethinyl estradiol/norgestrel label, contraindications… during pregnancy Current diagnosis or history of breast cancer, which may be hormone sensitive Hypersensitivity to any of the components of Turqoz Women who are receiving Hepatitis C drug combinations containing ombitasvir/paritaprevir/ritonavir, with or without dasabuvir, due to the potential for ALT elevations (see Warnings, Risk of liver enzyme elevations with concomitant hepatitis c treatment).
Ethinyl estradiol/norgestrel label, warningsRisk of Liver Enzyme Elevations with Concomitant Hepatitis C Treatment During clinical trials with the Hepatitis C combination drug regimen that contains ombitasvir/paritaprevir/ritonavir, with or without dasabuvir, ALT elevations greater than 5 times the upper limit of normal (ULN), including some cases greater than 20 times the ULN, were significantly more frequent in women using ethinyl estradiol-containing medications such as COCs.
Source: FDA drug label (Turqoz), Lupin Pharmaceuticals, Inc., effective December 5, 2025 (SPL set 5eecfd2c-4bda-4349-b634-199a354fa996), via openFDA; the full label on DailyMed
What does the ritonavir label say about ethinyl estradiol/norgestrel?
Ritonavir's label (effective July 23, 2026) does not name ethinyl estradiol/norgestrel in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Norvir), AbbVie Inc., effective July 23, 2026 (SPL set 2849298e-de6e-47bb-8194-56e075b33fc3), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Ethinyl estradiol/norgestrel | Ritonavir | |
|---|---|---|
| Labeled for | Birth control | HIV |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $0.302 per tablet 28 tablet | $0.607 per tablet 100 mg tablet |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once