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What the FDA labels say about taking them together

Ethinyl estradiol/norgestimate and nevirapine

Ethinyl estradiol/norgestimate's FDA label of February 6, 2026 names nevirapine in its drug interactions section; the nevirapine label PlainMeds reads does not name ethinyl estradiol/norgestimate. The ethinyl estradiol/norgestimate label: “Human immunodeficiency virus (HIV)/Hepatitis C virus (HCV) protease inhibitors, non-nucleoside reverse transcriptase inhibitors, and HIV/AIDS medications containing strong inhibitors or inducers of CYP3A Significant …”

Check it at the source: the ethinyl estradiol/norgestimate FDA label on DailyMed (effective February 6, 2026, Glenmark Pharmaceuticals Inc., USA); the nevirapine FDA label on DailyMed (effective July 15, 2026, Mylan Pharmaceuticals Inc.).

What does the ethinyl estradiol/norgestimate label say about nevirapine?

Ethinyl estradiol/norgestimate label, drug interactions

… lopinavir/ritonavir, and tipranavir/ritonavir] or increase [e.g., indinavir and atazanavir/ritonavir])/HCV protease inhibitors (decrease [e.g., boceprevir and telaprevir]) or with non-nucleoside reverse transcriptase inhibitors (decrease [e.g., nevirapine] or increase [e.g., etravirine]) or with HIV/AIDS medications containing strong inhibitors (e.g., cobicistat and ritonavir) or inducers of CYP3A.

Source: FDA drug label (Norgestimate and Ethinyl Estradiol), Glenmark Pharmaceuticals Inc., USA, effective February 6, 2026 (SPL set 8b247e46-203e-4f5b-b5a7-cbd57341c735), via openFDA; the full label on DailyMed

What does the nevirapine label say about ethinyl estradiol/norgestimate?

Nevirapine's label (effective July 15, 2026) does not name ethinyl estradiol/norgestimate in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Nevirapine), Mylan Pharmaceuticals Inc., effective July 15, 2026 (SPL set c6e93829-7024-48f6-8023-da6ff27dfc0a), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

18Ethinyl estradiol/norgestimate generic labelers
6Nevirapine generic labelers
Ethinyl estradiol/norgestimateNevirapine
Labeled forAcne, Birth controlHIV
Boxed warningYesYes
Pharmacy cost (NADAC)$0.115 per tablet 0.25-0.035 mg tablet$0.147 per tablet 200 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?