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What the FDA labels say about taking them together

Ethinyl estradiol/norgestimate and griseofulvin

Ethinyl estradiol/norgestimate's FDA label of February 6, 2026 names griseofulvin in its drug interactions section; the griseofulvin label PlainMeds reads does not name ethinyl estradiol/norgestimate. The ethinyl estradiol/norgestimate label: “Some drugs or herbal products that may decrease the effectiveness of hormonal contraceptives include phenytoin, barbiturates, carbamazepine, bosentan, felbamate, griseofulvin, oxcarbazepine, rifampicin, topiramate …”

Check it at the source: the ethinyl estradiol/norgestimate FDA label on DailyMed (effective February 6, 2026, Glenmark Pharmaceuticals Inc., USA); the griseofulvin FDA label on DailyMed (effective December 10, 2025).

What does the ethinyl estradiol/norgestimate label say about griseofulvin?

Ethinyl estradiol/norgestimate label, drug interactions

Some drugs or herbal products that may decrease the effectiveness of hormonal contraceptives include phenytoin, barbiturates, carbamazepine, bosentan, felbamate, griseofulvin, oxcarbazepine, rifampicin, topiramate, rifabutin, rufinamide, aprepitant, and products containing St. John’s wort.

Source: FDA drug label (Norgestimate and Ethinyl Estradiol), Glenmark Pharmaceuticals Inc., USA, effective February 6, 2026 (SPL set 8b247e46-203e-4f5b-b5a7-cbd57341c735), via openFDA; the full label on DailyMed

What does the griseofulvin label say about ethinyl estradiol/norgestimate?

Griseofulvin's label (effective December 10, 2025) does not name ethinyl estradiol/norgestimate in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Ultramicrosize Griseofulvin), Chartwell RX, LLC., effective December 10, 2025 (SPL set efb8a660-802c-4ca6-bbff-ad7b48b91aef), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

18Ethinyl estradiol/norgestimate generic labelers
10Griseofulvin generic labelers
Ethinyl estradiol/norgestimateGriseofulvin
Labeled forAcne, Birth controlFungal infections
Boxed warningYesNo
Pharmacy cost (NADAC)$0.115 per tablet 0.25-0.035 mg tablet$3.74 per tablet 250 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?