Estradiol · more major-labeled pairs than Ethinyl Estradiol
SPL labels Ethinyl Estradiol + Estradiol as minor; Ethinyl Estradiol 14 / Estradiol 50 in that band.
Mechanism on file: Taking these two medications together can slow down how your body breaks down estrogen. This can cause the level of estrogen in your blood to rise.
FDA SPL severity: Minor
Ethinyl Estradiol + Estradiol · SPL mechanism field
Taking these two medications together can slow down how your body breaks down estrogen. This can cause the level of estrogen in your blood to rise.
Minor band excerpt · Ethinyl Estradiol with Estradiol
7.2 Increase i n Plasma Levels of Ethinyl Estradiol Associated with Co-Administered Drugs Co-administration of atorvastatin and certain COCs containing ethinyl estradiol increase AUC values for ethinyl estradiol by approximately 20 percent. Ascorbic acid and acetaminophen may increase plasma ethinyl estradiol levels, possibly by inhibition of conjugation. 7.4 Changes in Plasma Levels of Co-Administered Drugs COCs containing some synthetic estrogens (for example, ethinyl estradiol) may inhibit the metabolism of other compounds.
Ethinyl Estradiol · 14 minor + 14 total pairs
- Acetaminophen minor
- Ascorbic Acid minor
- Atorvastatin minor
- Carbamazepine minor
Estradiol · 1 major-labeled pairs (vs Ethinyl Estradiol's 0)
- Acetaminophen minor
- Alosetron minor
- Amoxicillin minor
- Amoxicillin/Clavulanate minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.