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What the FDA labels say about taking them together

Ethinyl estradiol/ferrous fumarate/levonorgestrel and temazepam

Ethinyl estradiol/ferrous fumarate/levonorgestrel's FDA label of October 18, 2024 names temazepam in its drug interactions section; the temazepam label PlainMeds reads does not name ethinyl estradiol/ferrous fumarate/levonorgestrel. The ethinyl estradiol/ferrous fumarate/levonorgestrel label: “Combined oral contraceptives have been shown to decrease plasma concentrations of acetaminophen, clofibric acid, morphine, salicylic acid, temazepam and lamotrigine.”

Check it at the source: the ethinyl estradiol/ferrous fumarate/levonorgestrel FDA label on DailyMed (effective October 18, 2024, Xiromed, LLC); the temazepam FDA label on DailyMed (effective June 9, 2026).

What does the ethinyl estradiol/ferrous fumarate/levonorgestrel label say about temazepam?

Ethinyl estradiol/ferrous fumarate/levonorgestrel label, drug interactions

Combined oral contraceptives have been shown to decrease plasma concentrations of acetaminophen, clofibric acid, morphine, salicylic acid, temazepam and lamotrigine.

Source: FDA drug label (Joyeaux), Xiromed, LLC, effective October 18, 2024 (SPL set 655b2c93-cfae-d44f-c128-c816bbd88e45), via openFDA; the full label on DailyMed

What does the temazepam label say about ethinyl estradiol/ferrous fumarate/levonorgestrel?

Temazepam's label (effective June 9, 2026) does not name ethinyl estradiol/ferrous fumarate/levonorgestrel in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (RESTORIL), SpecGx LLC, effective June 9, 2026 (SPL set bc56f7fd-1aaf-48ff-8aa7-d467e59e1015), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

1Ethinyl estradiol/ferrous fumarate/levonorgestrel generic labelers
20Temazepam generic labelers
Ethinyl estradiol/ferrous fumarate/levonorgestrelTemazepam
Labeled forBirth controlInsomnia
Boxed warningYesYes
Pharmacy cost (NADAC)$3.45 per tablet 28 tablet$0.0767 per capsule 15 mg capsule
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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