What the FDA labels say about taking them together
Ethinyl estradiol/ferrous fumarate/levonorgestrel and rosuvastatin
Ethinyl estradiol/ferrous fumarate/levonorgestrel's FDA label of October 18, 2024 names rosuvastatin in its drug interactions section; the rosuvastatin labels PlainMeds reads (2) do not name ethinyl estradiol/ferrous fumarate/levonorgestrel. The ethinyl estradiol/ferrous fumarate/levonorgestrel label: “Substances increasing the plasma concentrations of COCs: Co-administration of atorvastatin or rosuvastatin and certain COCs containing EE increase AUC values for EE by approximately 20-25%.”
Check it at the source: the ethinyl estradiol/ferrous fumarate/levonorgestrel FDA label on DailyMed (effective October 18, 2024, Xiromed, LLC); the rosuvastatin FDA label on DailyMed (effective September 4, 2026, ScieGen Pharmaceuticals, Inc.).
What does the ethinyl estradiol/ferrous fumarate/levonorgestrel label say about rosuvastatin?
Ethinyl estradiol/ferrous fumarate/levonorgestrel label, drug interactionsSubstances increasing the plasma concentrations of COCs: Co-administration of atorvastatin or rosuvastatin and certain COCs containing EE increase AUC values for EE by approximately 20-25%.
Source: FDA drug label (Joyeaux), Xiromed, LLC, effective October 18, 2024 (SPL set 655b2c93-cfae-d44f-c128-c816bbd88e45), via openFDA; the full label on DailyMed
What does the rosuvastatin label say about ethinyl estradiol/ferrous fumarate/levonorgestrel?
Rosuvastatin's label (effective September 4, 2026) and its 1 other brand-application label do not name ethinyl estradiol/ferrous fumarate/levonorgestrel in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Rosuvastatin), ScieGen Pharmaceuticals, Inc., effective September 4, 2026 (SPL set ee4933c5-0d97-494d-ac0f-2083e0100836), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Ethinyl estradiol/ferrous fumarate/levonorgestrel | Rosuvastatin | |
|---|---|---|
| Labeled for | Birth control | Heart attack and coronary artery disease, High cholesterol, High triglycerides, Stroke prevention |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $3.45 per tablet 28 tablet | $0.0692 per tablet 40 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once