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What the FDA labels say about taking them together

Ethinyl estradiol/ferrous fumarate/levonorgestrel and nevirapine

Ethinyl estradiol/ferrous fumarate/levonorgestrel's FDA label of October 18, 2024 names nevirapine in its drug interactions section; the nevirapine label PlainMeds reads does not name ethinyl estradiol/ferrous fumarate/levonorgestrel. The ethinyl estradiol/ferrous fumarate/levonorgestrel label: “Significant changes (increase or decrease) in the plasma concentrations of estrogen and/or progestin have been noted in some cases of co-administration with HIV/HCV protease inhibitors and non-nucleoside reverse …”

Check it at the source: the ethinyl estradiol/ferrous fumarate/levonorgestrel FDA label on DailyMed (effective October 18, 2024, Xiromed, LLC); the nevirapine FDA label on DailyMed (effective July 15, 2026, Mylan Pharmaceuticals Inc.).

What does the ethinyl estradiol/ferrous fumarate/levonorgestrel label say about nevirapine?

Ethinyl estradiol/ferrous fumarate/levonorgestrel label, drug interactions

Significant changes (increase or decrease) in the plasma concentrations of estrogen and/or progestin have been noted in some cases of co-administration with HIV/HCV protease inhibitors and non-nucleoside reverse transcriptase inhibitors (decrease [e.g., nelfinavir, ritonavir, darunavir/ritonavir, (fos)amprenavir/ritonavir, lopinavir/ritonavir, tipranavir/ritonavir, boceprevir, telaprevir, nevirapine and efavirenz] or increase [e.g., indinavir, atazanavir/ritonavir and etravirine]).

Source: FDA drug label (Joyeaux), Xiromed, LLC, effective October 18, 2024 (SPL set 655b2c93-cfae-d44f-c128-c816bbd88e45), via openFDA; the full label on DailyMed

What does the nevirapine label say about ethinyl estradiol/ferrous fumarate/levonorgestrel?

Nevirapine's label (effective July 15, 2026) does not name ethinyl estradiol/ferrous fumarate/levonorgestrel in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Nevirapine), Mylan Pharmaceuticals Inc., effective July 15, 2026 (SPL set c6e93829-7024-48f6-8023-da6ff27dfc0a), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

1Ethinyl estradiol/ferrous fumarate/levonorgestrel generic labelers
6Nevirapine generic labelers
Ethinyl estradiol/ferrous fumarate/levonorgestrelNevirapine
Labeled forBirth controlHIV
Boxed warningYesYes
Pharmacy cost (NADAC)$3.45 per tablet 28 tablet$0.147 per tablet 200 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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