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What the FDA labels say about taking them together

Ethinyl estradiol/ferrous bisglycinate/levonorgestrel and etravirine

Ethinyl estradiol/ferrous bisglycinate/levonorgestrel's FDA label of January 9, 2025 names etravirine in its drug interactions section; the etravirine label PlainMeds reads does not name ethinyl estradiol/ferrous bisglycinate/levonorgestrel. The ethinyl estradiol/ferrous bisglycinate/levonorgestrel label: “Human Immunodeficiency Virus (HIV)/ Hepatitis C Virus (HCV) Protease Inhibitors and Non-nucleoside Reverse Transcriptase Inhibitors Significant changes (increase or decrease) in the plasma concentrations of estrogen …”

Check it at the source: the ethinyl estradiol/ferrous bisglycinate/levonorgestrel FDA label on DailyMed (effective January 9, 2025, Lupin Pharmaceuticals, Inc.); the etravirine FDA label on DailyMed (effective August 15, 2023, Janssen Products LP).

What does the ethinyl estradiol/ferrous bisglycinate/levonorgestrel label say about etravirine?

Ethinyl estradiol/ferrous bisglycinate/levonorgestrel label, drug interactions

Human Immunodeficiency Virus (HIV)/ Hepatitis C Virus (HCV) Protease Inhibitors and Non-nucleoside Reverse Transcriptase Inhibitors Significant changes (increase or decrease) in the plasma concentrations of estrogen and/or progestin have been noted in some cases of co-administration with HIV/HCV protease inhibitors and non- nucleoside reverse transcriptase inhibitors (decrease [e.g., nelfinavir, ritonavir, darunavir/ritonavir, (fos) amprenavir/ritonavir, lopinavir/ritonavir, tipranavir/ritonavir, boceprevir, telaprevir, nevirapine and efavirenz] or increase [e.g., indinavir, atazanavir/ritonavir and etravirine]).

Source: FDA drug label (MINZOYA), Lupin Pharmaceuticals, Inc., effective January 9, 2025 (SPL set d5ebd7fa-c388-4619-8dcb-e862e4ce5285), via openFDA; the full label on DailyMed

What does the etravirine label say about ethinyl estradiol/ferrous bisglycinate/levonorgestrel?

Etravirine's label (effective August 15, 2023) does not name ethinyl estradiol/ferrous bisglycinate/levonorgestrel in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Intelence), Janssen Products LP, effective August 15, 2023 (SPL set 6a9cbc29-9f15-4b24-8d86-206b82887f3d), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

1Ethinyl estradiol/ferrous bisglycinate/levonorgestrel generic labelers
5Etravirine generic labelers
Ethinyl estradiol/ferrous bisglycinate/levonorgestrelEtravirine
Labeled forBirth controlHIV
Boxed warningYesNo
Pharmacy cost (NADAC)$3.45 per tablet 28 tablet$9.94 per tablet 200 mg tablet
Shortage nowNo current entryA presentation being discontinued

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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