What the FDA labels say about taking them together
Ethinyl estradiol/etonogestrel and theophylline
Ethinyl estradiol/etonogestrel's FDA label of November 14, 2025 names theophylline in its drug interactions section; the theophylline label PlainMeds reads does not name ethinyl estradiol/etonogestrel. The ethinyl estradiol/etonogestrel label: “Effects of CHCs on Other Drugs CHCs containing ethinyl estradiol may inhibit the metabolism of other compounds and increase their plasma concentrations.”
Check it at the source: the ethinyl estradiol/etonogestrel FDA label on DailyMed (effective November 14, 2025, Organon LLC); the theophylline FDA label on DailyMed (effective March 10, 2026, Strides Pharma Science Limited).
What does the ethinyl estradiol/etonogestrel label say about theophylline?
Ethinyl estradiol/etonogestrel label, drug interactionsEffects of CHCs on Other Drugs CHCs containing ethinyl estradiol may inhibit the metabolism of other compounds (e.g., cyclosporine, prednisolone, theophylline, tizanidine, and voriconazole) and increase their plasma concentrations.
Source: FDA drug label (NuvaRing), Organon LLC, effective November 14, 2025 (SPL set 55eb60e3-6f4d-40a3-8ee6-e7fd2d0c7d97), via openFDA; the full label on DailyMed
What does the theophylline label say about ethinyl estradiol/etonogestrel?
Theophylline's label (effective March 10, 2026) does not name ethinyl estradiol/etonogestrel in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Theophylline), Strides Pharma Science Limited, effective March 10, 2026 (SPL set b7a90ccf-9c32-40cc-9008-7e55b3da4dfd), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Ethinyl estradiol/etonogestrel | Theophylline | |
|---|---|---|
| Labeled for | Birth control | Asthma |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $46.35 per ring Etonogestrel-ee vaginal ring | $0.330 per tablet 300 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once