What the FDA labels say about taking them together
Atorvastatin and ethinyl estradiol/etonogestrel
Ethinyl estradiol/etonogestrel's FDA label of November 14, 2025 names atorvastatin in its drug interactions section; the atorvastatin labels PlainMeds reads (2) do not name ethinyl estradiol/etonogestrel. The ethinyl estradiol/etonogestrel label: “Substances increasing the plasma concentrations of CHCs Co-administration of atorvastatin and certain CHCs containing ethinyl estradiol increase AUC values for ethinyl estradiol by approximately 20-25%.”
Check it at the source: the atorvastatin FDA label on DailyMed (effective April 15, 2024, Viatris Specialty LLC); the ethinyl estradiol/etonogestrel FDA label on DailyMed (effective November 14, 2025, Organon LLC).
What does the atorvastatin label say about ethinyl estradiol/etonogestrel?
Atorvastatin's label (effective April 15, 2024) and its 1 other brand-application label do not name ethinyl estradiol/etonogestrel in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Lipitor), NDA020702 (Upjohn), as published by Viatris Specialty LLC, effective April 15, 2024 (SPL set a60cc18b-0631-4cf0-b021-9f52224ece65), via openFDA; the full label on DailyMed
What does the ethinyl estradiol/etonogestrel label say about atorvastatin?
Ethinyl estradiol/etonogestrel label, drug interactionsSubstances increasing the plasma concentrations of CHCs Co-administration of atorvastatin and certain CHCs containing ethinyl estradiol increase AUC values for ethinyl estradiol by approximately 20-25%.
Source: FDA drug label (NuvaRing), Organon LLC, effective November 14, 2025 (SPL set 55eb60e3-6f4d-40a3-8ee6-e7fd2d0c7d97), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Atorvastatin | Ethinyl estradiol/etonogestrel | |
|---|---|---|
| Labeled for | High cholesterol, Angina, High triglycerides, Heart attack and coronary artery disease | Birth control |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $0.0228 per tablet 10 mg tablet | $46.35 per ring Etonogestrel-ee vaginal ring |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once