What the FDA labels say about taking them together
Etanercept and infliximab
Infliximab's FDA label of August 28, 2026 names etanercept in its warnings and precautions section; the etanercept label PlainMeds reads does not name infliximab.
Check it at the source: the etanercept FDA label on DailyMed (effective May 11, 2026, Immunex Corporation); the infliximab FDA label on DailyMed (effective August 28, 2026).
What does the etanercept label say about infliximab?
Etanercept's label (effective May 11, 2026) does not name infliximab in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (ENBREL), Immunex Corporation, effective May 11, 2026 (SPL set a002b40c-097d-47a5-957f-7a7b1807af7f), via openFDA; the full label on DailyMed
What does the infliximab label say about etanercept?
Infliximab label, warnings and precautionsBecause of the nature of the adverse reactions seen with the concurrent use of etanercept and anakinra therapy, similar toxicities may also result from the concurrent use of anakinra and other TNF blockers.
Source: FDA drug label (Renflexis), Organon LLC, effective August 28, 2026 (SPL set dbf738c4-3fac-4422-a9d8-51d9c83a8789), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Etanercept | Infliximab | |
|---|---|---|
| Labeled for | Rheumatoid arthritis, Psoriasis | Rheumatoid arthritis, Crohn's disease and ulcerative colitis |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $2,084.14 per mL 25 mg/0.5 mL syringe | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once