What the FDA labels say about taking them together
Eszopiclone and lorazepam
Eszopiclone's FDA label of January 30, 2026 names lorazepam in its drug interactions section; the lorazepam labels PlainMeds reads (3) do not name eszopiclone. The eszopiclone label: “Eszopiclone and lorazepam decreased each other’s C max by 22%.”
Check it at the source: the eszopiclone FDA label on DailyMed (effective January 30, 2026, Glenmark Pharmaceuticals Inc. USA); the lorazepam FDA label on DailyMed (effective July 9, 2025, Bausch Health US LLC).
What does the eszopiclone label say about lorazepam?
Eszopiclone label, drug interactionsEszopiclone and lorazepam decreased each other’s C max by 22%.
Source: FDA drug label (Eszopiclone), Glenmark Pharmaceuticals Inc. USA, effective January 30, 2026 (SPL set 584dc66c-063a-4552-a056-74b811e2bc80), via openFDA; the full label on DailyMed
What does the lorazepam label say about eszopiclone?
Lorazepam's label (effective July 9, 2025) and its 2 other brand-application labels do not name eszopiclone in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Ativan), Bausch Health US LLC, effective July 9, 2025 (SPL set 89057c93-8155-4040-acec-64e877bd2b4c), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Eszopiclone | Lorazepam | |
|---|---|---|
| Labeled for | Insomnia | Anxiety |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $0.0993 per tablet 1 mg tablet | $0.0344 per tablet 0.5 mg tablet |
| Shortage now | No current entry | In shortage |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once