What the FDA labels say about taking them together
Escitalopram and gilteritinib
Gilteritinib's FDA label of January 1, 2022 names escitalopram in its drug interactions section; the escitalopram labels PlainMeds reads (2) do not name gilteritinib. The gilteritinib label: “Drugs that Target 5HT2B Receptor or Sigma Nonspecific Receptor Concomitant use of gilteritinib may reduce the effects of drugs that target the 5HT 2B receptor or the sigma nonspecific receptor.”
Check it at the source: the escitalopram FDA label on DailyMed (effective October 1, 2023, Allergan, Inc.); the gilteritinib FDA label on DailyMed (effective January 1, 2022, Astellas Pharma US, Inc.).
What does the escitalopram label say about gilteritinib?
Escitalopram's label (effective October 1, 2023) and its 1 other brand-application label do not name gilteritinib in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Lexapro), NDA021323 (Abbvie), as published by Allergan, Inc., effective October 1, 2023 (SPL set 13bb8267-1cab-43e5-acae-55a4d957630a), via openFDA; the full label on DailyMed
What does the gilteritinib label say about escitalopram?
Gilteritinib label, drug interactionsDrugs that Target 5HT2B Receptor or Sigma Nonspecific Receptor Concomitant use of gilteritinib may reduce the effects of drugs that target the 5HT 2B receptor or the sigma nonspecific receptor (e.g., escitalopram, fluoxetine, sertraline).
Source: FDA drug label (Xospata), Astellas Pharma US, Inc., effective January 1, 2022 (SPL set b5ff59aa-9c0d-49a8-9053-1f179b482383), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Escitalopram | Gilteritinib | |
|---|---|---|
| Labeled for | Depression, Anxiety | n/a |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $0.0632 per tablet 20 mg tablet | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once