What the FDA labels say about taking them together
Erythromycin and silodosin
Silodosin's FDA label of April 15, 2026 names erythromycin in its drug interactions section; the erythromycin labels PlainMeds reads (4) do not name silodosin. The silodosin label: “Concomitant administration with moderate CYP3A4 inhibitors may increase concentration of silodosin.”
Check it at the source: the erythromycin FDA label on DailyMed (effective August 1, 2024, Teva Pharmaceuticals USA, Inc.); the silodosin FDA label on DailyMed (effective April 15, 2026, Amneal Pharmaceuticals NY LLC).
What does the erythromycin label say about silodosin?
Erythromycin's label (effective August 1, 2024) and its 3 other brand-application labels do not name silodosin in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Erythromycin), Teva Pharmaceuticals USA, Inc., effective August 1, 2024 (SPL set 75a0bd5a-d09f-483b-bfd8-f8343b149eb2), via openFDA; the full label on DailyMed
What does the silodosin label say about erythromycin?
Silodosin label, drug interactionsConcomitant administration with moderate CYP3A4 inhibitors (e.g., diltiazem, erythromycin, verapamil) may increase concentration of silodosin.
Source: FDA drug label (Silodosin), Amneal Pharmaceuticals NY LLC, effective April 15, 2026 (SPL set de619e27-9384-4b86-abdc-de0557cd39e8), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Erythromycin | Silodosin | |
|---|---|---|
| Labeled for | Bacterial infections, Acne | Enlarged prostate (BPH) |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $1.96 per tablet 250 mg tablet | $0.319 per capsule 8 mg capsule |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once