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What the FDA labels say about taking them together

Erythromycin and multiple vitamins

Multiple vitamins's FDA label of November 20, 2024 names erythromycin in its drug interactions section; the erythromycin labels PlainMeds reads (4) do not name multiple vitamins. The multiple vitamins label: “Thiamine, riboflavin, pyridoxine, niacinamide, and ascorbic acid decrease activities of erythromycin, kanamycin, streptomycin, doxycycline, and lincomycin”

Check it at the source: the erythromycin FDA label on DailyMed (effective August 1, 2024, Teva Pharmaceuticals USA, Inc.); the multiple vitamins FDA label on DailyMed (effective November 20, 2024).

What does the erythromycin label say about multiple vitamins?

Erythromycin's label (effective August 1, 2024) and its 3 other brand-application labels do not name multiple vitamins in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Erythromycin), Teva Pharmaceuticals USA, Inc., effective August 1, 2024 (SPL set 75a0bd5a-d09f-483b-bfd8-f8343b149eb2), via openFDA; the full label on DailyMed

What does the multiple vitamins label say about erythromycin?

Multiple vitamins label, drug interactions

Effect of INFUVITE PEDIATRIC on other drugs: Thiamine, riboflavin, pyridoxine, niacinamide, and ascorbic acid decrease activities of erythromycin, kanamycin, streptomycin, doxycycline, and lincomycin

Source: FDA drug label (Infuvite Adult, NDA021163), Sandoz Inc, effective November 6, 2024 (SPL set 14c7bfc5-07e8-400f-b8ff-5e4794dd2805), via openFDA

Source: FDA drug label (Infuvite Pediatric), Sandoz Inc, effective November 20, 2024 (SPL set 6d06546e-8b0a-4490-82d9-397bd902a044), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

38Erythromycin generic labelers
0Multiple vitamins generic labelers
ErythromycinMultiple vitamins
Labeled forBacterial infections, Acnen/a
Boxed warningNoNo
Pharmacy cost (NADAC)$1.96 per tablet 250 mg tabletn/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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