What the FDA labels say about taking them together
Erlotinib and vonoprazan
Vonoprazan's FDA label of July 16, 2026 names erlotinib in its drug interactions section; the erlotinib label PlainMeds reads does not name vonoprazan. The vonoprazan label: “Other Drugs Clinical Effect Vonoprazan reduces intragastric acidity, which may decrease the absorption of drugs reducing their effectiveness.”
Check it at the source: the erlotinib FDA label on DailyMed (effective June 10, 2024, Alembic Pharmaceuticals Limited); the vonoprazan FDA label on DailyMed (effective July 16, 2026, Phathom Pharmaceuticals Inc.).
What does the erlotinib label say about vonoprazan?
Erlotinib's label (effective June 10, 2024) does not name vonoprazan in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (ERLOTINIB HYDROCHLORIDE), Alembic Pharmaceuticals Limited, effective June 10, 2024 (SPL set ab6f3cb3-34a8-4492-a5d7-fb6b055a2d6b), via openFDA; the full label on DailyMed
What does the vonoprazan label say about erlotinib?
Vonoprazan label, drug interactionsOther Drugs (e.g., iron salts, erlotinib, dasatinib, nilotinib, mycophenolate mofetil, ketoconazole/itraconazole) Clinical Effect Vonoprazan reduces intragastric acidity [see Clinical Pharmacology (12.2) ], which may decrease the absorption of drugs reducing their effectiveness.
Source: FDA drug label (VOQUEZNA), Phathom Pharmaceuticals Inc., effective July 16, 2026 (SPL set 0cc52ac5-77ec-4d66-a770-762a1a960914), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Erlotinib | Vonoprazan | |
|---|---|---|
| Labeled for | Lung cancer | Acid reflux and ulcers |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | n/a | $22.41 per tablet 20 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once