What the FDA labels say about taking them together
Epirubicin and paclitaxel
Epirubicin's FDA label of July 24, 2026 names paclitaxel in its drug interactions section; the paclitaxel labels PlainMeds reads (4) do not name epirubicin. The epirubicin label: “The administration of epirubicin immediately prior to or after paclitaxel increased the systemic exposure of epirubicin, epirubicinol and 7-deoxydoxorubicin aglycone.”
Check it at the source: the epirubicin FDA label on DailyMed (effective July 24, 2026, Pharmacia & Upjohn Company LLC); the paclitaxel FDA label on DailyMed (effective January 21, 2026, Natco Pharma USA LLC).
What does the epirubicin label say about paclitaxel?
Epirubicin label, drug interactionsThe administration of epirubicin immediately prior to or after paclitaxel increased the systemic exposure of epirubicin, epirubicinol and 7-deoxydoxorubicin aglycone [see Clinical Pharmacology (12.3) ].
Source: FDA drug label (Ellence), NDA050778 (Pfizer Inc), as published by Pharmacia & Upjohn Company LLC, effective July 24, 2026 (SPL set 0a03c798-a652-4895-b29c-3b521a89ba42), via openFDA; the full label on DailyMed
What does the paclitaxel label say about epirubicin?
Paclitaxel's label (effective January 21, 2026) and its 3 other brand-application labels do not name epirubicin in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Paclitaxel), Natco Pharma USA LLC, effective January 21, 2026 (SPL set a1eb16b4-285b-4e81-9c4e-1244d4a52af8), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Epirubicin | Paclitaxel | |
|---|---|---|
| Labeled for | n/a | Breast cancer, Lung cancer |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | n/a | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once