What the FDA labels say about taking them together
Epinephrine and tividenofusp alfa
Tividenofusp alfa's FDA label of March 20, 2026 names epinephrine in its boxed warning section; the epinephrine labels PlainMeds reads (4) do not name tividenofusp alfa. The tividenofusp alfa label: “… and immediately initiate appropriate medical treatment, including use of epinephrine.”
Check it at the source: the epinephrine FDA label on DailyMed (effective July 13, 2026, A-S Medication Solutions); the tividenofusp alfa FDA label on DailyMed (effective March 20, 2026).
What does the epinephrine label say about tividenofusp alfa?
Epinephrine's label (effective July 13, 2026) and its 3 other brand-application labels do not name tividenofusp alfa in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Epinephrine), A-S Medication Solutions, effective July 13, 2026 (SPL set 6e811e28-0199-4df7-a916-5940c632401d), via openFDA; the full label on DailyMed
What does the tividenofusp alfa label say about epinephrine?
Tividenofusp alfa label, boxed warningAnaphylaxis has occurred during the early course of enzyme replacement therapy and after extended duration of therapy. ( 5.1 ) Initiate AVLAYAH in a healthcare setting with appropriate medical monitoring and support measures, including access to cardiopulmonary resuscitation equipment. ( 5.1 ) If a severe hypersensitivity reaction (e.g., anaphylaxis) occurs, discontinue AVLAYAH and immediately initiate appropriate medical treatment, including use of epinephrine.
Tividenofusp alfa label, warnings and precautionsIf a severe hypersensitivity reaction (including anaphylaxis) occurs, discontinue AVLAYAH and immediately initiate appropriate medical treatment, including use of epinephrine.
Source: FDA drug label (AVLAYAH), Denali Therapeutics Inc., effective March 20, 2026 (SPL set 014d92c1-b643-4680-8ca6-f0b3307da915), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Epinephrine | Tividenofusp alfa | |
|---|---|---|
| Labeled for | Asthma | n/a |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $123.51 per unit 0.15 mg auto-injct | n/a |
| Shortage now | A presentation being discontinued | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once