What the FDA labels say about taking them together
Epinephrine and remifentanil
Remifentanil's FDA label of December 15, 2025 names epinephrine in its warnings and precautions section; the epinephrine labels PlainMeds reads (4) do not name remifentanil. The remifentanil label: “If volume expansion with fluids plus other countermeasures do not correct hypotension, consider administration of pressor agents other than epinephrine.”
Check it at the source: the epinephrine FDA label on DailyMed (effective July 13, 2026, A-S Medication Solutions); the remifentanil FDA label on DailyMed (effective December 15, 2025, Mylan Institutional LLC).
What does the epinephrine label say about remifentanil?
Epinephrine's label (effective July 13, 2026) and its 3 other brand-application labels do not name remifentanil in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Epinephrine), A-S Medication Solutions, effective July 13, 2026 (SPL set 6e811e28-0199-4df7-a916-5940c632401d), via openFDA; the full label on DailyMed
What does the remifentanil label say about epinephrine?
Remifentanil label, warnings and precautionsIf volume expansion with fluids plus other countermeasures do not correct hypotension, consider administration of pressor agents other than epinephrine.
Source: FDA drug label (Ultiva), Mylan Institutional LLC, effective December 15, 2025 (SPL set 4dbcb8f9-1987-4b66-bd2f-d251fda0be10), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Epinephrine | Remifentanil | |
|---|---|---|
| Labeled for | Asthma | n/a |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $123.51 per unit 0.15 mg auto-injct | n/a |
| Shortage now | A presentation being discontinued | In shortage |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once