What the FDA labels say about taking them together
Epinephrine and margetuximab
Margetuximab's FDA label of February 11, 2025 names epinephrine in its warnings and precautions section; the epinephrine labels PlainMeds reads (4) do not name margetuximab. The margetuximab label: “Interrupt MARGENZA infusion in patients experiencing dyspnea or clinically significant hypotension and intervene with medical therapy which may include epinephrine, corticosteroids, diphenhydramine, bronchodilators and …”
Check it at the source: the epinephrine FDA label on DailyMed (effective July 13, 2026, A-S Medication Solutions); the margetuximab FDA label on DailyMed (effective February 11, 2025).
What does the epinephrine label say about margetuximab?
Epinephrine's label (effective July 13, 2026) and its 3 other brand-application labels do not name margetuximab in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Epinephrine), A-S Medication Solutions, effective July 13, 2026 (SPL set 6e811e28-0199-4df7-a916-5940c632401d), via openFDA; the full label on DailyMed
What does the margetuximab label say about epinephrine?
Margetuximab label, warnings and precautionsInterrupt MARGENZA infusion in patients experiencing dyspnea or clinically significant hypotension and intervene with medical therapy which may include epinephrine, corticosteroids, diphenhydramine, bronchodilators and oxygen.
Source: FDA drug label (MARGENZA), TerSera Therapeutics LLC, effective February 11, 2025 (SPL set 6a6d50c7-06ea-479c-83cc-f197a9e428c9), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Epinephrine | Margetuximab | |
|---|---|---|
| Labeled for | Asthma | Breast cancer |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $123.51 per unit 0.15 mg auto-injct | n/a |
| Shortage now | A presentation being discontinued | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once