What the FDA labels say about taking them together
Epinephrine and loxapine
Loxapine's FDA label (Adasuve) of July 6, 2026 names epinephrine in its warnings and precautions section; the epinephrine labels PlainMeds reads (4) do not name loxapine. The loxapine label: “Epinephrine should not be used, because beta stimulation may worsen hypotension in the setting of ADASUVE-induced partial alpha blockade.”
Check it at the source: the epinephrine FDA label on DailyMed (effective July 13, 2026, A-S Medication Solutions); the loxapine FDA label on DailyMed (effective February 26, 2025, Elite Laboratories, Inc.).
What does the epinephrine label say about loxapine?
Epinephrine's label (effective July 13, 2026) and its 3 other brand-application labels do not name loxapine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Epinephrine), A-S Medication Solutions, effective July 13, 2026 (SPL set 6e811e28-0199-4df7-a916-5940c632401d), via openFDA; the full label on DailyMed
What does the loxapine label say about epinephrine?
Adasuve label (Alexza Pharmaceuticals, Inc., July 6, 2026), warnings and precautionsEpinephrine should not be used, because beta stimulation may worsen hypotension in the setting of ADASUVE-induced partial alpha blockade.
Source: FDA drug label (Adasuve, NDA022549), Alexza Pharmaceuticals, Inc., effective July 6, 2026 (SPL set 50e11732-7387-452d-b3e6-db3a431d5c4a), via openFDA
Source: FDA drug label (Loxapine), Elite Laboratories, Inc., effective February 26, 2025 (SPL set a0cc7bb6-075f-47d1-8935-eb77a29d8c45), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Epinephrine | Loxapine | |
|---|---|---|
| Labeled for | Asthma | Schizophrenia |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $123.51 per unit 0.15 mg auto-injct | $0.468 per capsule 10 mg capsule |
| Shortage now | A presentation being discontinued | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once