What the FDA labels say about taking them together
Epinephrine and iodixanol
Iodixanol's FDA label of October 10, 2025 names epinephrine in its drug interactions section; the epinephrine labels PlainMeds reads (4) do not name iodixanol. The iodixanol label: “… reduces the responsiveness of treatment of hypersensitivity reactions with epinephrine.”
Check it at the source: the epinephrine FDA label on DailyMed (effective July 13, 2026, A-S Medication Solutions); the iodixanol FDA label on DailyMed (effective October 10, 2025, GE Healthcare Inc.).
What does the epinephrine label say about iodixanol?
Epinephrine's label (effective July 13, 2026) and its 3 other brand-application labels do not name iodixanol in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Epinephrine), A-S Medication Solutions, effective July 13, 2026 (SPL set 6e811e28-0199-4df7-a916-5940c632401d), via openFDA; the full label on DailyMed
What does the iodixanol label say about epinephrine?
Iodixanol label, drug interactionsBeta-adrenergic Blocking Agents The use of beta-adrenergic blocking agents lowers the threshold for and increases the severity of contrast reactions, and reduces the responsiveness of treatment of hypersensitivity reactions with epinephrine.
Source: FDA drug label (Visipaque), GE Healthcare Inc., effective October 10, 2025 (SPL set e9d87b8c-7695-4c0f-8e81-000dedb5f66d), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Epinephrine | Iodixanol | |
|---|---|---|
| Labeled for | Asthma | n/a |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $123.51 per unit 0.15 mg auto-injct | n/a |
| Shortage now | A presentation being discontinued | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once