What the FDA labels say about taking them together
Epinephrine and hydrochlorothiazide/quinapril
Hydrochlorothiazide/quinapril's FDA label of December 11, 2023 names epinephrine in its warnings section; the epinephrine labels PlainMeds reads (4) do not name hydrochlorothiazide/quinapril.
Check it at the source: the epinephrine FDA label on DailyMed (effective July 13, 2026, A-S Medication Solutions); the hydrochlorothiazide/quinapril FDA label on DailyMed (effective December 11, 2023, Chartwell RX, LLC).
What does the epinephrine label say about hydrochlorothiazide/quinapril?
Epinephrine's label (effective July 13, 2026) and its 3 other brand-application labels do not name hydrochlorothiazide/quinapril in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Epinephrine), A-S Medication Solutions, effective July 13, 2026 (SPL set 6e811e28-0199-4df7-a916-5940c632401d), via openFDA; the full label on DailyMed
What does the hydrochlorothiazide/quinapril label say about epinephrine?
Hydrochlorothiazide/quinapril label, warningsWhere there is involvement of the tongue, glottis, or larynx likely to cause airway obstruction, emergency therapy including, but not limited to, subcutaneous epinephrine solution 1:1000 (0.3 to 0.5 mL) should be promptly administered (see PRECAUTIONS and ADVERSE REACTIONS ).
Source: FDA drug label (Quinapril and Hydrochlorothiazide), Chartwell RX, LLC, effective December 11, 2023 (SPL set 2eae533f-d0af-47e8-a1f2-94bc8cc89b5a), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Epinephrine | Hydrochlorothiazide/quinapril | |
|---|---|---|
| Labeled for | Asthma | High blood pressure |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $123.51 per unit 0.15 mg auto-injct | n/a |
| Shortage now | A presentation being discontinued | In shortage |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once