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What the FDA labels say about taking them together

Ephedrine and triamcinolone

Triamcinolone's FDA label (Triesence) of June 5, 2026 names ephedrine in its drug interactions section; the ephedrine labels PlainMeds reads (4) do not name triamcinolone. The triamcinolone label: “CYP 3A4 inducers: Drugs, such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance metabolism of corticosteroid and require that the dosage …”

Check it at the source: the ephedrine FDA label on DailyMed (effective September 16, 2024, Nexus Pharmaceuticals, LLC); the triamcinolone FDA label on DailyMed (effective January 28, 2026, E. Fougera & Co. a division of Fougera Pharmaceuticals, LLC).

What does the ephedrine label say about triamcinolone?

Ephedrine's label (effective September 16, 2024) and its 3 other brand-application labels do not name triamcinolone in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Emerphed PFS), Nexus Pharmaceuticals, LLC, effective September 16, 2024 (SPL set 14601778-93ac-43ec-b66b-5a942317133f), via openFDA; the full label on DailyMed

What does the triamcinolone label say about ephedrine?

Triesence label (Harrow Eye, LLC, June 5, 2026), drug interactions

CYP 3A4 inducers (e.g., barbiturates, phenytoin, carbamazepine, and rifampin): Drugs, such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance metabolism of corticosteroid and require that the dosage of corticosteroid be increased.

Source: FDA drug label (Triesence, NDA022048), Harrow Eye, LLC, effective June 5, 2026 (SPL set 2267978c-72ad-9229-e063-6394a90a09d0), via openFDA

Source: FDA drug label (triamcinolone acetonide), E. Fougera & Co. a division of Fougera Pharmaceuticals, LLC, effective January 28, 2026 (SPL set 92a1ded0-8e1a-4994-9c8a-89e84fc85c94), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

19Ephedrine generic labelers
73Triamcinolone generic labelers
EphedrineTriamcinolone
Labeled forAsthmaAsthma, Eczema (atopic dermatitis), Anemia, Leukemia, lymphoma and myeloma, Allergies, Fever, Pain, Osteoarthritis
Boxed warningNoNo
Pharmacy cost (NADAC)n/a$0.0452 per gram 0.1% cream
Shortage nowNo current entryListed; available

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?