What the FDA labels say about taking them together
Entrectinib and itraconazole
Itraconazole's FDA label of July 13, 2026 names entrectinib in its drug interactions section; the entrectinib label PlainMeds reads does not name itraconazole.
Check it at the source: the entrectinib FDA label on DailyMed (effective December 4, 2025, Genentech, Inc.); the itraconazole FDA label on DailyMed (effective July 13, 2026, Janssen Pharmaceuticals, Inc.).
What does the entrectinib label say about itraconazole?
Entrectinib's label (effective December 4, 2025) does not name itraconazole in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Rozlytrek), Genentech, Inc., effective December 4, 2025 (SPL set c7c71b0c-2549-4495-86b6-c2807fa54908), via openFDA; the full label on DailyMed
What does the itraconazole label say about entrectinib?
Itraconazole label, drug interactionsEntrectinib Pemigatinib Talazoparib Refer to the entrectinib, pemigatinib and talazoparib prescribing information for dosing instructions if concomitant use cannot be avoided.
Source: FDA drug label (SPORANOX), Janssen Pharmaceuticals, Inc., effective July 13, 2026 (SPL set a4d555fa-787c-40fb-bb7d-b0d4f7318fd0), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Entrectinib | Itraconazole | |
|---|---|---|
| Labeled for | Lung cancer | Fungal infections |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | n/a | $0.910 per capsule 100 mg capsule |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once