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What the FDA labels say about taking them together

Emtricitabine/tenofovir alafenamide and ritonavir

Emtricitabine/tenofovir alafenamide's FDA label of July 7, 2026 names ritonavir in its drug interactions section; the ritonavir label PlainMeds reads does not name emtricitabine/tenofovir alafenamide. The emtricitabine/tenofovir alafenamide label: “Coadministration with DESCOVY is not recommended.”

Check it at the source: the emtricitabine/tenofovir alafenamide FDA label on DailyMed (effective July 7, 2026, Gilead Sciences, Inc.); the ritonavir FDA label on DailyMed (effective July 23, 2026, AbbVie Inc.).

What does the emtricitabine/tenofovir alafenamide label say about ritonavir?

Emtricitabine/tenofovir alafenamide label, drug interactions

Concomitant Drug Class/Drug Name: tipranavir/ritonavir; Effect on Concentration ↓=Decrease: ↓ TAF; Clinical Comment: Coadministration with DESCOVY is not recommended.

Source: FDA drug label (DESCOVY), Gilead Sciences, Inc., effective July 7, 2026 (SPL set 06f66e98-e6ee-4538-9506-6c1282cc14c1), via openFDA; the full label on DailyMed

What does the ritonavir label say about emtricitabine/tenofovir alafenamide?

Ritonavir's label (effective July 23, 2026) does not name emtricitabine/tenofovir alafenamide in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Norvir), AbbVie Inc., effective July 23, 2026 (SPL set 2849298e-de6e-47bb-8194-56e075b33fc3), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Emtricitabine/tenofovir alafenamide generic labelers
7Ritonavir generic labelers
Emtricitabine/tenofovir alafenamideRitonavir
Labeled forHIVHIV
Boxed warningYesYes
Pharmacy cost (NADAC)$74.94 per tablet 200-25 mg tablet$0.607 per tablet 100 mg tablet
Shortage nowNo current entryA presentation being discontinued

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?