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What the FDA labels say about taking them together

Eltrombopag and ubrogepant

Ubrogepant's FDA label of June 5, 2025 names eltrombopag in its drug interactions section; the eltrombopag labels PlainMeds reads (2) do not name ubrogepant. The ubrogepant label: “Use of BCRP and/or P-gp only inhibitors may increase the exposure of ubrogepant [ s ee Clinical Pharmacology ].”

Check it at the source: the eltrombopag FDA label on DailyMed (effective December 18, 2025, Novartis Pharmaceuticals Corporation); the ubrogepant FDA label on DailyMed (effective June 5, 2025, Allergan, Inc.).

What does the eltrombopag label say about ubrogepant?

Eltrombopag's label (effective December 18, 2025) and its 1 other brand-application label do not name ubrogepant in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (PROMACTA), Novartis Pharmaceuticals Corporation, effective December 18, 2025 (SPL set 7714a0ed-34bb-46e6-a0a5-b363908b22c2), via openFDA; the full label on DailyMed

What does the ubrogepant label say about eltrombopag?

Ubrogepant label, drug interactions

Use of BCRP and/or P-gp only inhibitors (e.g., quinidine, carvedilol, eltrombopag, curcumin) may increase the exposure of ubrogepant [ s ee Clinical Pharmacology ( 12.3 ) ].

Source: FDA drug label (UBRELVY), NDA211765 (Abbvie), as published by Allergan, Inc., effective June 5, 2025 (SPL set fd9f9458-fd96-4688-be3f-f77b3d1af6ab), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

13Eltrombopag generic labelers
0Ubrogepant generic labelers
EltrombopagUbrogepant
Labeled forAnemiaMigraine
Boxed warningYesNo
Pharmacy cost (NADAC)$25.85 per tablet 50 mg tablet$109.11 per tablet 100 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?