What the FDA labels say about taking them together
Eltrombopag and ribavirin
Eltrombopag's FDA label of December 18, 2025 names ribavirin in its boxed warning section; the ribavirin labels PlainMeds reads (2) do not name eltrombopag. The eltrombopag label: “… patients with chronic hepatitis C, ALVAIZ in combination with interferon and ribavirin may increase the risk of hepatic decompensation.”
Check it at the source: the eltrombopag FDA label on DailyMed (effective December 18, 2025, Novartis Pharmaceuticals Corporation); the ribavirin FDA label on DailyMed (effective February 6, 2024, Aurobindo Pharma Limited).
What does the eltrombopag label say about ribavirin?
Eltrombopag label, boxed warningRISK FOR HEPATIC DECOMPENSATION IN PATIENTS WITH CHRONIC HEPATITIS C and RISK OF HEPATOTOXICITY In patients with chronic hepatitis C, PROMACTA in combination with interferon and ribavirin may increase the risk of hepatic decompensation [see Warnings and Precautions (5.1)].
Eltrombopag label, warnings and precautionsDecompensation in Patients With Chronic Hepatitis C In patients with chronic hepatitis C, PROMACTA in combination with interferon and ribavirin may increase the risk of hepatic decompensation.
Source: FDA drug label (Alvaiz, NDA216774), Teva Pharmaceuticals, Inc., effective January 1, 2026 (SPL set ed51e463-7a03-4858-bbd2-882ce4753d5a), via openFDA
Source: FDA drug label (PROMACTA), Novartis Pharmaceuticals Corporation, effective December 18, 2025 (SPL set 7714a0ed-34bb-46e6-a0a5-b363908b22c2), via openFDA; the full label on DailyMed
What does the ribavirin label say about eltrombopag?
Ribavirin's label (effective February 6, 2024) and its 1 other brand-application label do not name eltrombopag in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Ribavirin), Aurobindo Pharma Limited, effective February 6, 2024 (SPL set eee304d0-c2ea-44f4-97d9-92a414d31b6c), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Eltrombopag | Ribavirin | |
|---|---|---|
| Labeled for | Anemia | Hepatitis C |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $25.85 per tablet 50 mg tablet | $0.451 per tablet 200 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once