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What the FDA labels say about taking them together

Eltrombopag and repaglinide

Eltrombopag's FDA label of December 18, 2025 names repaglinide in its drug interactions section; the repaglinide label PlainMeds reads does not name eltrombopag.

Check it at the source: the eltrombopag FDA label on DailyMed (effective December 18, 2025, Novartis Pharmaceuticals Corporation); the repaglinide FDA label on DailyMed (effective May 2, 2025, Chartwell RX, LLC).

What does the eltrombopag label say about repaglinide?

Eltrombopag label, drug interactions

Use caution when concomitantly administering PROMACTA and drugs that are substrates of OATP1B1 (e.g., atorvastatin, bosentan, ezetimibe, fluvastatin, glyburide, olmesartan, pitavastatin, pravastatin, rosuvastatin, repaglinide, rifampin, simvastatin acid, SN-38 [active metabolite of irinotecan], valsartan) or breast cancer resistance protein (BCRP) (e.g., imatinib, irinotecan, lapatinib, methotrexate, mitoxantrone, rosuvastatin, sulfasalazine, topotecan).

Source: FDA drug label (Alvaiz, NDA216774), Teva Pharmaceuticals, Inc., effective January 1, 2026 (SPL set ed51e463-7a03-4858-bbd2-882ce4753d5a), via openFDA

Source: FDA drug label (PROMACTA), Novartis Pharmaceuticals Corporation, effective December 18, 2025 (SPL set 7714a0ed-34bb-46e6-a0a5-b363908b22c2), via openFDA; the full label on DailyMed

What does the repaglinide label say about eltrombopag?

Repaglinide's label (effective May 2, 2025) does not name eltrombopag in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Repaglinide), Chartwell RX, LLC, effective May 2, 2025 (SPL set cb995e92-295e-4638-a064-978211f5afe1), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

13Eltrombopag generic labelers
7Repaglinide generic labelers
EltrombopagRepaglinide
Labeled forAnemiaType 2 diabetes
Boxed warningYesNo
Pharmacy cost (NADAC)$25.85 per tablet 50 mg tablet$0.0987 per tablet 1 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?