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What the FDA labels say about taking them together

Eltrombopag and pravastatin

Eltrombopag's FDA label of December 18, 2025 names pravastatin in its drug interactions section; the pravastatin label PlainMeds reads does not name eltrombopag.

Check it at the source: the eltrombopag FDA label on DailyMed (effective December 18, 2025, Novartis Pharmaceuticals Corporation); the pravastatin FDA label on DailyMed (effective July 31, 2026, Apotex Corp.).

What does the eltrombopag label say about pravastatin?

Eltrombopag label, drug interactions

Use caution when concomitantly administering PROMACTA and drugs that are substrates of OATP1B1 (e.g., atorvastatin, bosentan, ezetimibe, fluvastatin, glyburide, olmesartan, pitavastatin, pravastatin, rosuvastatin, repaglinide, rifampin, simvastatin acid, SN-38 [active metabolite of irinotecan], valsartan) or breast cancer resistance protein (BCRP) (e.g., imatinib, irinotecan, lapatinib, methotrexate, mitoxantrone, rosuvastatin, sulfasalazine, topotecan).

Source: FDA drug label (Alvaiz, NDA216774), Teva Pharmaceuticals, Inc., effective January 1, 2026 (SPL set ed51e463-7a03-4858-bbd2-882ce4753d5a), via openFDA

Source: FDA drug label (PROMACTA), Novartis Pharmaceuticals Corporation, effective December 18, 2025 (SPL set 7714a0ed-34bb-46e6-a0a5-b363908b22c2), via openFDA; the full label on DailyMed

What does the pravastatin label say about eltrombopag?

Pravastatin's label (effective July 31, 2026) does not name eltrombopag in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (PRAVASTATIN SODIUM), Apotex Corp., effective July 31, 2026 (SPL set dcf45e4f-b46e-6fbb-b67a-2ff619ab1780), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

13Eltrombopag generic labelers
37Pravastatin generic labelers
EltrombopagPravastatin
Labeled forAnemiaHeart attack and coronary artery disease, High cholesterol, High triglycerides
Boxed warningYesNo
Pharmacy cost (NADAC)$25.85 per tablet 50 mg tablet$0.058 per tablet 20 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?