What the FDA labels say about taking them together
Eliglustat and sotalol
Eliglustat's FDA label of March 3, 2024 names sotalol in its warnings and precautions section; the sotalol labels PlainMeds reads (3) do not name eliglustat. The eliglustat label: “Avoid use of CERDELGA in patients with: pre-existing cardiac disease long QT syndrome in combination with Class IA or Class III antiarrhythmic medications”
Check it at the source: the eliglustat FDA label on DailyMed (effective March 3, 2024, Genzyme Corporation); the sotalol FDA label on DailyMed (effective December 16, 2024, Legacy Pharma USA, Inc.).
What does the eliglustat label say about sotalol?
Eliglustat label, warnings and precautionsAvoid use of CERDELGA in patients with: pre-existing cardiac disease (congestive heart failure, recent acute myocardial infarction, bradycardia, heart block, ventricular arrhythmia) long QT syndrome in combination with Class IA (e.g., quinidine, procainamide) or Class III (e.g., amiodarone, sotalol) antiarrhythmic medications [see Clinical Pharmacology (12.2) ]
Source: FDA drug label (Cerdelga), Genzyme Corporation, effective March 3, 2024 (SPL set 819f828a-b888-4e46-83fc-94d774a28a83), via openFDA; the full label on DailyMed
What does the sotalol label say about eliglustat?
Sotalol's label (effective December 16, 2024) and its 2 other brand-application labels do not name eliglustat in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (BETAPACE), Legacy Pharma USA, Inc., effective December 16, 2024 (SPL set a6a7702f-36c9-45db-b640-453dc324baee), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Eliglustat | Sotalol | |
|---|---|---|
| Labeled for | n/a | Atrial fibrillation |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | n/a | $0.0707 per tablet 80 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once