What the FDA labels say about taking them together
Eliglustat and procainamide
Eliglustat's FDA label of March 3, 2024 names procainamide in its warnings and precautions section; the procainamide label PlainMeds reads does not name eliglustat. The eliglustat label: “Avoid use of CERDELGA in patients with: pre-existing cardiac disease long QT syndrome in combination with Class IA or Class III antiarrhythmic medications”
Check it at the source: the eliglustat FDA label on DailyMed (effective March 3, 2024, Genzyme Corporation); the procainamide FDA label on DailyMed (effective February 17, 2025, Caplin Steriles Limited).
What does the eliglustat label say about procainamide?
Eliglustat label, warnings and precautionsAvoid use of CERDELGA in patients with: pre-existing cardiac disease (congestive heart failure, recent acute myocardial infarction, bradycardia, heart block, ventricular arrhythmia) long QT syndrome in combination with Class IA (e.g., quinidine, procainamide) or Class III (e.g., amiodarone, sotalol) antiarrhythmic medications [see Clinical Pharmacology (12.2) ]
Source: FDA drug label (Cerdelga), Genzyme Corporation, effective March 3, 2024 (SPL set 819f828a-b888-4e46-83fc-94d774a28a83), via openFDA; the full label on DailyMed
What does the procainamide label say about eliglustat?
Procainamide's label (effective February 17, 2025) does not name eliglustat in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Procainamide Hydrochloride), Caplin Steriles Limited, effective February 17, 2025 (SPL set fcaa5e9a-3c8a-4796-aa87-626268b6cf60), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Eliglustat | Procainamide | |
|---|---|---|
| Labeled for | n/a | n/a |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | n/a | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once