What the FDA labels say about taking them together
Elbasvir/grazoprevir and lovastatin
Elbasvir/grazoprevir's FDA label of March 13, 2026 names lovastatin in its drug interactions section; the lovastatin label PlainMeds reads does not name elbasvir/grazoprevir. The elbasvir/grazoprevir label: “Statin-associated adverse events such as myopathy should be closely monitored. The lowest necessary dose should be used when co-administered with ZEPATIER.”
Check it at the source: the elbasvir/grazoprevir FDA label on DailyMed (effective March 13, 2026, Merck Sharp & Dohme LLC); the lovastatin FDA label on DailyMed (effective May 6, 2026, Lupin Pharmaceuticals, Inc.).
What does the elbasvir/grazoprevir label say about lovastatin?
Elbasvir/grazoprevir label, drug interactionsConcomitant Drug Class/Drug Name: Fluvastatin Lovastatin Simvastatin; Effect on Concentration ↓ = decrease, ↑ = increase: ↑ fluvastatin ↑ lovastatin ↑ simvastatin; Clinical Comment: Statin-associated adverse events such as myopathy should be closely monitored. The lowest necessary dose should be used when co-administered with ZEPATIER.
Source: FDA drug label (ZEPATIER), Merck Sharp & Dohme LLC, effective March 13, 2026 (SPL set 164dc02a-9180-426a-b8b5-04ab39d2bbd4), via openFDA; the full label on DailyMed
What does the lovastatin label say about elbasvir/grazoprevir?
Lovastatin's label (effective May 6, 2026) does not name elbasvir/grazoprevir in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Lovastatin), Lupin Pharmaceuticals, Inc., effective May 6, 2026 (SPL set df7ddf4f-d569-431e-81f1-9129d7043150), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Elbasvir/grazoprevir | Lovastatin | |
|---|---|---|
| Labeled for | Hepatitis C | High cholesterol, Heart attack and coronary artery disease |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | n/a | $0.0436 per tablet 20 mg tablet |
| Shortage now | A presentation being discontinued | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once