What the FDA labels say about taking them together
Elbasvir/grazoprevir and fluvastatin
Elbasvir/grazoprevir's FDA label of March 13, 2026 names fluvastatin in its drug interactions section; the fluvastatin labels PlainMeds reads (2) do not name elbasvir/grazoprevir. The elbasvir/grazoprevir label: “Statin-associated adverse events such as myopathy should be closely monitored. The lowest necessary dose should be used when co-administered with ZEPATIER.”
Check it at the source: the elbasvir/grazoprevir FDA label on DailyMed (effective March 13, 2026, Merck Sharp & Dohme LLC); the fluvastatin FDA label on DailyMed (effective April 21, 2025, Teva Pharmaceuticals USA, Inc.).
What does the elbasvir/grazoprevir label say about fluvastatin?
Elbasvir/grazoprevir label, drug interactionsConcomitant Drug Class/Drug Name: Fluvastatin Lovastatin Simvastatin; Effect on Concentration ↓ = decrease, ↑ = increase: ↑ fluvastatin ↑ lovastatin ↑ simvastatin; Clinical Comment: Statin-associated adverse events such as myopathy should be closely monitored. The lowest necessary dose should be used when co-administered with ZEPATIER.
Source: FDA drug label (ZEPATIER), Merck Sharp & Dohme LLC, effective March 13, 2026 (SPL set 164dc02a-9180-426a-b8b5-04ab39d2bbd4), via openFDA; the full label on DailyMed
What does the fluvastatin label say about elbasvir/grazoprevir?
Fluvastatin's label (effective April 21, 2025) and its 1 other brand-application label do not name elbasvir/grazoprevir in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Fluvastatin), Teva Pharmaceuticals USA, Inc., effective April 21, 2025 (SPL set aad8b373-0aec-4efb-8e61-3d8114b31127), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Elbasvir/grazoprevir | Fluvastatin | |
|---|---|---|
| Labeled for | Hepatitis C | High cholesterol |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | n/a | $2.88 per tablet 80 mg tablet |
| Shortage now | A presentation being discontinued | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once